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Pancreatic Neuroendocrine Tumors in Mice Deficient in Proglucagon-Derived Peptides

Animal models with defective glucagon action show hyperplasia of islet α-cells, however, the regulatory mechanisms underlying the proliferation of islet endocrine cells remain largely to be elucidated. The Gcg(gfp/gfp) mice, which are homozygous for glucagon/green fluorescent protein knock-in allele...

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Detalles Bibliográficos
Autores principales:	Takano, Yuko, Kasai, Kenji, Takagishi, Yoshiko, Kikumori, Toyone, Imai, Tsuneo, Murata, Yoshiharu, Hayashi, Yoshitaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508046/ https://www.ncbi.nlm.nih.gov/pubmed/26192435 http://dx.doi.org/10.1371/journal.pone.0133812

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