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Structural Basis for the Inhibition of a Phospholipase A(2)-Like Toxin by Caffeic and Aristolochic Acids

One of the main challenges in toxicology today is to develop therapeutic alternatives for the treatment of snake venom injuries that are not efficiently neutralized by conventional serum therapy. Venom phospholipases A(2) (PLA(2)s) and PLA(2)-like proteins play a fundamental role in skeletal muscle...

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Detalles Bibliográficos
Autores principales: Fernandes, Carlos A. H., Cardoso, Fábio Florença, Cavalcante, Walter G. L., Soares, Andreimar M., Dal-Pai, Maeli, Gallacci, Marcia, Fontes, Marcos R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508052/
https://www.ncbi.nlm.nih.gov/pubmed/26192963
http://dx.doi.org/10.1371/journal.pone.0133370