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B7-H3 silencing by RNAi inhibits tumor progression and enhances chemosensitivity in U937 cells

BACKGROUND: The role of B7-H3 in acute monocytic leukemia U937 cells has not been thoroughly investigated. MATERIALS AND METHODS: B7-H3 knockdown in the U937 cell line was performed using small hairpin (sh)RNA lentivirus transduction. The effects on cell proliferation, cycle, migration, and invasion...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Wang, Jing, Wang, Yanfang, Dong, Fei, Zhu, Mingxia, Wan, Wenli, Li, Haishen, Wu, Feifei, Yan, Xinxing, Ke, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508088/
https://www.ncbi.nlm.nih.gov/pubmed/26203263
http://dx.doi.org/10.2147/OTT.S85272