RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response

BACKGROUND: The heat shock response (HSR) is an ancient and highly conserved program of stress-induced gene expression, aimed at reestablishing protein homeostasis to preserve cellular fitness. Cells that fail to activate or maintain this protective response are hypersensitive to proteotoxic stress....

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Detalles Bibliográficos
Autores principales: Meijering, Roelien A. M., Wiersma, Marit, van Marion, Denise M. S., Zhang, Deli, Hoogstra-Berends, Femke, Dijkhuis, Anne-Jan, Schmidt, Martina, Wieland, Thomas, Kampinga, Harm H., Henning, Robert H., Brundel, Bianca J. J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508109/
https://www.ncbi.nlm.nih.gov/pubmed/26193369
http://dx.doi.org/10.1371/journal.pone.0133553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508109/
https://www.ncbi.nlm.nih.gov/pubmed/26193369
http://dx.doi.org/10.1371/journal.pone.0133553

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