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Valsartan ameliorates ageing-induced aorta degeneration via angiotensin II type 1 receptor-mediated ERK activity

Angiotensin II (Ang II) plays important roles in ageing-related disorders through its type 1 receptor (AT(1)R). However, the role and underlying mechanisms of AT1R in ageing-related vascular degeneration are not well understood. In this study, 40 ageing rats were randomly divided into two groups: ag...

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Detalles Bibliográficos
Autores principales: Shan, HaiYan, Zhang, Siyang, Li, Xuelian, yu, Kai, Zhao, Xin, Chen, Xinyue, Jin, Bo, Bai, XiaoJuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508146/
https://www.ncbi.nlm.nih.gov/pubmed/24548645
http://dx.doi.org/10.1111/jcmm.12251