Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell

The purpose of the present study was to clarify roles of cytosolic chloride ion (Cl(−)) in regulation of lysosomal acidification [intra-lysosomal pH (pH(lys))] and autophagy function in human gastric cancer cell line (MKN28). The MKN28 cells cultured under a low Cl(−) condition elevated pH(lys) and...

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Detalles Bibliográficos
Autores principales: Hosogi, Shigekuni, Kusuzaki, Katsuyuki, Inui, Toshio, Wang, Xiangdong, Marunaka, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508152/
https://www.ncbi.nlm.nih.gov/pubmed/24725767
http://dx.doi.org/10.1111/jcmm.12257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508152/
https://www.ncbi.nlm.nih.gov/pubmed/24725767
http://dx.doi.org/10.1111/jcmm.12257

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