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Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell
The purpose of the present study was to clarify roles of cytosolic chloride ion (Cl(−)) in regulation of lysosomal acidification [intra-lysosomal pH (pH(lys))] and autophagy function in human gastric cancer cell line (MKN28). The MKN28 cells cultured under a low Cl(−) condition elevated pH(lys) and...
Autores principales: | Hosogi, Shigekuni, Kusuzaki, Katsuyuki, Inui, Toshio, Wang, Xiangdong, Marunaka, Yoshinori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508152/ https://www.ncbi.nlm.nih.gov/pubmed/24725767 http://dx.doi.org/10.1111/jcmm.12257 |
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