XBP1S, a BMP2-inducible transcription factor, accelerates endochondral bone growth by activating GEP growth factor

We previously reported that transcription factor XBP1S binds to RUNX2 and enhances chondrocyte hypertrophy through acting as a cofactor of RUNX2. Herein, we report that XBP1S is a key downstream molecule of BMP2 and is required for BMP2-mediated chondrocyte differentiation. XBP1S is up-regulated dur...

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Detalles Bibliográficos
Autores principales: Guo, Feng-Jin, Xiong, Zhangyuan, Han, Xiaofeng, Liu, Chuanju, Liu, Yanna, Jiang, Rong, Zhang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508155/
https://www.ncbi.nlm.nih.gov/pubmed/24636354
http://dx.doi.org/10.1111/jcmm.12261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508155/
https://www.ncbi.nlm.nih.gov/pubmed/24636354
http://dx.doi.org/10.1111/jcmm.12261

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