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XBP1S, a BMP2-inducible transcription factor, accelerates endochondral bone growth by activating GEP growth factor
We previously reported that transcription factor XBP1S binds to RUNX2 and enhances chondrocyte hypertrophy through acting as a cofactor of RUNX2. Herein, we report that XBP1S is a key downstream molecule of BMP2 and is required for BMP2-mediated chondrocyte differentiation. XBP1S is up-regulated dur...
Autores principales: | Guo, Feng-Jin, Xiong, Zhangyuan, Han, Xiaofeng, Liu, Chuanju, Liu, Yanna, Jiang, Rong, Zhang, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508155/ https://www.ncbi.nlm.nih.gov/pubmed/24636354 http://dx.doi.org/10.1111/jcmm.12261 |
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