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Glucagon-Like Peptide-1 Increases Mitochondrial Biogenesis and Function in INS-1 Rat Insulinoma Cells

Glucagon-like peptide-1 (GLP-1) is a gut-derived incretin hormone that increases glucose-stimulated insulin secretion in pancreatic β-cells. Since mitochondrial function is crucial to insulin secretion, we hypothesized that GLP-1 may increase mitochondrial biogenesis in pancreatic β-cells. We treate...

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Detalles Bibliográficos
Autores principales: Kang, Mi Yeon, Oh, Tae Jung, Cho, Young Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508267/
https://www.ncbi.nlm.nih.gov/pubmed/26194081
http://dx.doi.org/10.3803/EnM.2015.30.2.216