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Cooperation of distinct Rac-dependent pathways to stabilise E-cadherin adhesion

The precise mechanisms via which Rac1 is activated by cadherin junctions are not fully known. In keratinocytes Rac1 activation by cadherin junctions requires EGFR signalling, but how EGFR does so is unclear. To address which activator could mediate E-cadherin signalling to Rac1, we investigated EGFR...

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Detalles Bibliográficos
Autores principales: Erasmus, Jennifer C., Welsh, Natalie J., Braga, Vania M.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508347/
https://www.ncbi.nlm.nih.gov/pubmed/25957131
http://dx.doi.org/10.1016/j.cellsig.2015.04.014