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The Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human Cancers

A normal evolution of the cell-cycle phases consists of multiple consecutive events, which makes it a highly complex process. Its preservation is regulated by Cyclin-Cdks (cyclin-dependent kinases) interactions and protein degradation, which is often controlled by the ubiquitin-mediated proteolysis....

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Detalles Bibliográficos
Autores principales: BOCHIS, OVIDIU VASILE, FETICA, BOGDAN, VLAD, CATALIN, ACHIMAS-CADARIU, PATRICIU, IRIMIE, ALEXANDRU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iuliu Hatieganu University of Medicine and Pharmacy 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508606/
https://www.ncbi.nlm.nih.gov/pubmed/26528041
http://dx.doi.org/10.15386/cjmed-377