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The pain receptor TRPV1 displays agonist-dependent activation stoichiometry

The receptor channel TRPV1 (Transient Receptor Potential Vanilloid 1) is expressed by primary afferent sensory neurons of the pain pathway, where it functions as a sensor of noxious heat and various chemicals, including eicosanoids, capsaicin, protons and peptide toxins. Comprised of four identical...

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Detalles Bibliográficos
Autores principales: Hazan, Adina, Kumar, Rakesh, Matzner, Henry, Priel, Avi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508619/
https://www.ncbi.nlm.nih.gov/pubmed/26194846
http://dx.doi.org/10.1038/srep12278