Network analysis of immunotherapy-induced regressing tumours identifies novel synergistic drug combinations

Cancer immunotherapy has shown impressive results, but most patients do not respond. We hypothesized that the effector response in the tumour could be visualized as a complex network of interacting gene products and that by mapping this network we could predict effective pharmacological intervention...

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Detalles Bibliográficos
Autores principales: Lesterhuis, W. Joost, Rinaldi, Catherine, Jones, Anya, Rozali, Esdy N., Dick, Ian M., Khong, Andrea, Boon, Louis, Robinson, Bruce W., Nowak, Anna K., Bosco, Anthony, Lake, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508665/
https://www.ncbi.nlm.nih.gov/pubmed/26193793
http://dx.doi.org/10.1038/srep12298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508665/
https://www.ncbi.nlm.nih.gov/pubmed/26193793
http://dx.doi.org/10.1038/srep12298

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