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Hyperosmotic stress activates the expression of members of the miR-15/107 family and induces downregulation of anti-apoptotic genes in rat liver

microRNAs are an abundant class of small non-coding RNAs that negatively regulate gene expression. Importantly, microRNA activity has been linked to the control of cellular stress response. In the present study, we investigated whether the expression of hepatic microRNAs is affected by changes in am...

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Detalles Bibliográficos
Autores principales: Santosa, David, Castoldi, Mirco, Paluschinski, Martha, Sommerfeld, Annika, Häussinger, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508667/
https://www.ncbi.nlm.nih.gov/pubmed/26195352
http://dx.doi.org/10.1038/srep12292