BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

Based on its in vitro unwinding activity on G-quadruplex (G4) DNA, the Bloom syndrome–associated helicase BLM is proposed to participate in telomere replication by aiding fork progression through G-rich telomeric DNA. Single molecule analysis of replicated DNA (SMARD) was used to determine the contr...

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Detalles Bibliográficos
Autores principales: Drosopoulos, William C., Kosiyatrakul, Settapong T., Schildkraut, Carl L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508891/
https://www.ncbi.nlm.nih.gov/pubmed/26195664
http://dx.doi.org/10.1083/jcb.201410061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508891/
https://www.ncbi.nlm.nih.gov/pubmed/26195664
http://dx.doi.org/10.1083/jcb.201410061

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