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Rme-8 depletion perturbs Notch recycling and predisposes to pathogenic signaling
Notch signaling is a major regulator of cell fate, proliferation, and differentiation. Like other signaling pathways, its activity is strongly influenced by intracellular trafficking. Besides contributing to signal activation and down-regulation, differential fluxes between trafficking routes can ca...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508892/ https://www.ncbi.nlm.nih.gov/pubmed/26169355 http://dx.doi.org/10.1083/jcb.201411001 |