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Analysis of the interplay of protein biogenesis factors at the ribosome exit site reveals new role for NAC

The ribosome exit site is a focal point for the interaction of protein-biogenesis factors that guide the fate of nascent polypeptides. These factors include chaperones such as NAC, N-terminal-modifying enzymes like Methionine aminopeptidase (MetAP), and the signal recognition particle (SRP), which t...

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Detalles Bibliográficos
Autores principales: Nyathi, Yvonne, Pool, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508901/
https://www.ncbi.nlm.nih.gov/pubmed/26195668
http://dx.doi.org/10.1083/jcb.201410086