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Runs of homozygosity and distribution of functional variants in the cattle genome

BACKGROUND: Recent developments in sequencing technology have facilitated widespread investigations of genomic variants, including continuous stretches of homozygous genomic regions. For cattle, a large proportion of these runs of homozygosity (ROH) are likely the result of inbreeding due to the acc...

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Detalles Bibliográficos
Autores principales: Zhang, Qianqian, Guldbrandtsen, Bernt, Bosse, Mirte, Lund, Mogens S, Sahana, Goutam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508970/
https://www.ncbi.nlm.nih.gov/pubmed/26198692
http://dx.doi.org/10.1186/s12864-015-1715-x