Acquired resistance to decitabine and cross-resistance to gemcitabine during the long-term treatment of human HCT116 colorectal cancer cells with decitabine

The aim of the present study was to determine the effects of long-term exposure of decitabine (DAC) to HCT116 colorectal cancer (CRC) cells on the acquisition of resistance to DAC as well as cross-resistance to anticancer drugs used for CRC or other epigenetic modifiers. In the present study, DAC-re...

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Detalles Bibliográficos
Autores principales: HOSOKAWA, MIKA, SAITO, MAI, NAKANO, AIKO, IWASHITA, SAKURA, ISHIZAKA, AYANO, UEDA, KUMIKO, IWAKAWA, SEIGO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509010/
https://www.ncbi.nlm.nih.gov/pubmed/26622566
http://dx.doi.org/10.3892/ol.2015.3253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509010/
https://www.ncbi.nlm.nih.gov/pubmed/26622566
http://dx.doi.org/10.3892/ol.2015.3253

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