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The integral membrane protein ITM2A, a transcriptional target of PKA-CREB, regulates autophagic flux via interaction with the vacuolar ATPase

The PKA-CREB signaling pathway is involved in many cellular processes including autophagy. Recent studies demonstrated that PKA-CREB inhibits autophagy in yeast; however, the role of PKA-CREB signaling in mammalian cell autophagy has not been fully characterized. Here, we report that the integral me...

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Detalles Bibliográficos
Autores principales: Namkoong, Sim, Lee, Kang Il, Lee, Jin I, Park, Rackhyun, Lee, Eun-Ju, Jang, Ik-Soon, Park, Junsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509440/
https://www.ncbi.nlm.nih.gov/pubmed/25951193
http://dx.doi.org/10.1080/15548627.2015.1034412