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Divergent roles of BECN1 in LC3 lipidation and autophagosomal function

BECN1/Beclin 1 is regarded as a critical component in the class III phosphatidylinositol 3-kinase (PtdIns3K) complex to trigger autophagy in mammalian cells. Despite its significant role in a number of cellular and physiological processes, the exact function of BECN1 in autophagy remains controversi...

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Detalles Bibliográficos
Autores principales: He, Ruina, Peng, Jingyu, Yuan, Pengfei, Xu, Fang, Wei, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509441/
https://www.ncbi.nlm.nih.gov/pubmed/25955014
http://dx.doi.org/10.1080/15548627.2015.1034404