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Route of antigen delivery impacts the immunostimulatory activity of dendritic cell-based vaccines for hepatocellular carcinoma

BACKGROUND: Dendritic cells (DC) are uniquely equipped to capture, process, and present antigens from their environment. The context in which an antigen is acquired by DC helps to dictate the subsequent immune response. Cancer vaccination promotes antitumor immunity by directing an immune response t...

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Detalles Bibliográficos
Autores principales: Pardee, Angela D., Yano, Hiroshi, Weinstein, Aliyah M., Ponce, Aaron A. K., Ethridge, Alexander D., Normolle, Daniel P., Vujanovic, Lazar, Mizejewski, Gerald J., Watkins, Simon C., Butterfield, Lisa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509479/
https://www.ncbi.nlm.nih.gov/pubmed/26199728
http://dx.doi.org/10.1186/s40425-015-0077-x