Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment

The mycobacterial ESX-1 virulence locus accelerates macrophage recruitment to the forming tuberculous granuloma. Newly recruited macrophages phagocytose previously infected apoptotic macrophages to become new bacterial growth niches. Granuloma macrophages can then necrose, releasing mycobacteria int...

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Detalles Bibliográficos
Autores principales: Pagán, Antonio J., Yang, Chao-Tsung, Cameron, James, Swaim, Laura E., Ellett, Felix, Lieschke, Graham J., Ramakrishnan, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509513/
https://www.ncbi.nlm.nih.gov/pubmed/26159717
http://dx.doi.org/10.1016/j.chom.2015.06.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509513/
https://www.ncbi.nlm.nih.gov/pubmed/26159717
http://dx.doi.org/10.1016/j.chom.2015.06.008

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