Enhanced therapeutic efficacy of budesonide in experimental colitis with enzyme/pH dual-sensitive polymeric nanoparticles

Current colon-targeted drug-delivery approaches for colitis therapy often utilize single pH-triggered systems, which are less reliable due to the variation of gut pH in individuals and in disease conditions. Herein, we prepared budesonide-loaded dual-sensitive nanoparticles using enzyme-sensitive az...

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Detalles Bibliográficos
Autores principales: Naeem, Muhammad, Cao, Jiafu, Choi, Moonjeong, Kim, Woo Seong, Moon, Hyung Ryong, Lee, Bok Luel, Kim, Min-Soo, Jung, Yunjin, Yoo, Jin-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509535/
https://www.ncbi.nlm.nih.gov/pubmed/26213469
http://dx.doi.org/10.2147/IJN.S87816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509535/
https://www.ncbi.nlm.nih.gov/pubmed/26213469
http://dx.doi.org/10.2147/IJN.S87816

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