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Enhanced therapeutic efficacy of budesonide in experimental colitis with enzyme/pH dual-sensitive polymeric nanoparticles

Current colon-targeted drug-delivery approaches for colitis therapy often utilize single pH-triggered systems, which are less reliable due to the variation of gut pH in individuals and in disease conditions. Herein, we prepared budesonide-loaded dual-sensitive nanoparticles using enzyme-sensitive az...

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Detalles Bibliográficos
Autores principales:	Naeem, Muhammad, Cao, Jiafu, Choi, Moonjeong, Kim, Woo Seong, Moon, Hyung Ryong, Lee, Bok Luel, Kim, Min-Soo, Jung, Yunjin, Yoo, Jin-Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509535/ https://www.ncbi.nlm.nih.gov/pubmed/26213469 http://dx.doi.org/10.2147/IJN.S87816

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