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Wakefulness Is Governed by GABA and Histamine Cotransmission

Histaminergic neurons in the tuberomammilary nucleus (TMN) of the hypothalamus form a widely projecting, wake-active network that sustains arousal. Yet most histaminergic neurons contain GABA. Selective siRNA knockdown of the vesicular GABA transporter (vgat, SLC32A1) in histaminergic neurons produc...

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Detalles Bibliográficos
Autores principales: Yu, Xiao, Ye, Zhiwen, Houston, Catriona M., Zecharia, Anna Y., Ma, Ying, Zhang, Zhe, Uygun, David S., Parker, Susan, Vyssotski, Alexei L., Yustos, Raquel, Franks, Nicholas P., Brickley, Stephen G., Wisden, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509551/
https://www.ncbi.nlm.nih.gov/pubmed/26094607
http://dx.doi.org/10.1016/j.neuron.2015.06.003