Phthalimide analogs as probable 15-lipoxygenase-1 inhibitors: synthesis, biological evaluation and docking studies

BACKGROUND: Recent studies have been explained the role of lipoxygenases (LOX) in the origin of cancer. Among the lipoxygenases, the 5-LOX, 12-LOX and 15-LOX are more important in the cause of neoplastic disorders. In the present investigation, a new series of anticancer agents with 1,3,4-thiadiazol...

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Detalles Bibliográficos
Autores principales: Aliabadi, Alireza, Mohammadi-Farani, Ahmad, Hosseinzadeh, Zeinab, Nadri, Hamid, Moradi, Alireza, Ahmadi, Farahnaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509565/
https://www.ncbi.nlm.nih.gov/pubmed/26197788
http://dx.doi.org/10.1186/s40199-015-0118-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509565/
https://www.ncbi.nlm.nih.gov/pubmed/26197788
http://dx.doi.org/10.1186/s40199-015-0118-5

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