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Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells

Transposable elements (TEs) comprise roughly forty per cent of mammalian genomes(1). TEs have played an active role in genetic variation, adaptation, and evolution through the duplication or deletion of genes or their regulatory elements(2-4) and TEs themselves can act as alternative promoters for n...

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Detalles Bibliográficos
Autores principales: Elsässer, Simon J, Noh, Kyung-Min, Diaz, Nichole, Allis, C David, Banaszynski, Laura A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509593/
https://www.ncbi.nlm.nih.gov/pubmed/25938714
http://dx.doi.org/10.1038/nature14345