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Impact of genetic similarity on imputation accuracy

BACKGROUND: Genotype imputation is a common technique in genetic research. Genetic similarity between target population and reference dataset is crucial for high-quality results. Although several reference panels are available, it is often not clear which is the most optimal for a particular target...

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Detalles Bibliográficos
Autores principales: Roshyara, Nab Raj, Scholz, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509609/
https://www.ncbi.nlm.nih.gov/pubmed/26193934
http://dx.doi.org/10.1186/s12863-015-0248-2