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Multivariate Meta-Analysis of Genetic Association Studies: A Simulation Study

In a meta-analysis with multiple end points of interests that are correlated between or within studies, multivariate approach to meta-analysis has a potential to produce more precise estimates of effects by exploiting the correlation structure between end points. However, under random-effects assump...

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Detalles Bibliográficos
Autores principales: Neupane, Binod, Beyene, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509672/
https://www.ncbi.nlm.nih.gov/pubmed/26196398
http://dx.doi.org/10.1371/journal.pone.0133243