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New classes of self-cleaving ribozymes revealed by comparative genomics analysis

Enzymes made of RNA catalyze reactions that are essential for protein synthesis and RNA processing. However, such natural ribozymes are exceedingly rare, as evident by the fact that the discovery rate for new classes has dropped to one per decade from about one per year during the 1980s. Indeed, onl...

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Detalles Bibliográficos
Autores principales: Weinberg, Zasha, Kim, Peter B., Chen, Tony H., Li, Sanshu, Harris, Kimberly A., Lünse, Christina E., Breaker, Ronald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509812/
https://www.ncbi.nlm.nih.gov/pubmed/26167874
http://dx.doi.org/10.1038/nchembio.1846