Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation

Interferon-γ (IFN-γ) primes macrophages for enhanced inflammatory activation by Toll-like receptors (TLRs) and microbial killing, but little is known about the regulation of cell metabolism or mRNA translation during priming. We found that IFN-γ regulates human macrophage metabolism and translation...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Xiaodi, Yu, Yingpu, Zhong, Yi, Giannopoulou, Eugenia G., Hu, Xiaoyu, Liu, Hui, Cross, Justin R., Rätsch, Gunnar, Rice, Charles M., Ivashkiv, Lionel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509841/
https://www.ncbi.nlm.nih.gov/pubmed/26147685
http://dx.doi.org/10.1038/ni.3205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509841/
https://www.ncbi.nlm.nih.gov/pubmed/26147685
http://dx.doi.org/10.1038/ni.3205

Ejemplares similares