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Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation

Interferon-γ (IFN-γ) primes macrophages for enhanced inflammatory activation by Toll-like receptors (TLRs) and microbial killing, but little is known about the regulation of cell metabolism or mRNA translation during priming. We found that IFN-γ regulates human macrophage metabolism and translation...

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Detalles Bibliográficos
Autores principales:	Su, Xiaodi, Yu, Yingpu, Zhong, Yi, Giannopoulou, Eugenia G., Hu, Xiaoyu, Liu, Hui, Cross, Justin R., Rätsch, Gunnar, Rice, Charles M., Ivashkiv, Lionel B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509841/ https://www.ncbi.nlm.nih.gov/pubmed/26147685 http://dx.doi.org/10.1038/ni.3205

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