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Splicing remodels the let-7 primary microRNA to facilitate Drosha processing in Caenorhabditis elegans
MicroRNAs (miRNAs) are a class of small noncoding RNAs that use partial base-pairing to recognize and regulate the expression of messenger RNAs (mRNAs). Mature miRNAs arise from longer primary transcripts (pri-miRNAs) that are processed to a shorter hairpin precursor miRNA (pre-miRNA) by the Micropr...
Autores principales: | Mondol, Vanessa, Ahn, Byoung Chan, Pasquinelli, Amy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509930/ https://www.ncbi.nlm.nih.gov/pubmed/26081559 http://dx.doi.org/10.1261/rna.052118.115 |
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