Inhibition of janus kinase 2 by compound AG490 suppresses the proliferation of MDA-MB-231 cells via up-regulating SARI (suppressor of AP-1, regulated by IFN)

OBJECTIVE(S): The Janus kinase-signal transducers and activators of transcription signaling pathway (JAK/STAT pathway) play an important role in proliferation of breast cancer cells. Previous data showed that inhibition of STAT3 suppresses the growth of breast cancer cells, but the associated mechan...

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Detalles Bibliográficos
Autores principales: Zhang, Yan-xia, Yan, Li, Liu, Guang-yu, Chen, Wen-jun, Gong, Wei-hong, Yu, Jin-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509956/
https://www.ncbi.nlm.nih.gov/pubmed/26221484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509956/
https://www.ncbi.nlm.nih.gov/pubmed/26221484

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