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Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites

Long interspersed elements (LINEs), through both self-mobilization and trans-mobilization of short interspersed elements and processed pseudogenes, have made an indelible impact on the structure and function of the human genome. One consequence is the creation of new CpG islands (CGIs). In fact, mor...

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Detalles Bibliográficos
Autores principales: Grandi, Fiorella C., Rosser, James M., Newkirk, Simon J., Yin, Jun, Jiang, Xiaoling, Xing, Zhuo, Whitmore, Leanne, Bashir, Sanum, Ivics, Zoltán, Izsvák, Zsuzsanna, Ye, Ping, Yu, Y. Eugene, An, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509998/
https://www.ncbi.nlm.nih.gov/pubmed/25995269
http://dx.doi.org/10.1101/gr.185132.114