Genome-wide activities of Polycomb complexes control pervasive transcription

Polycomb group (PcG) complexes PRC1 and PRC2 are well known for silencing specific developmental genes. PRC2 is a methyltransferase targeting histone H3K27 and producing H3K27me3, essential for stable silencing. Less well known but quantitatively much more important is the genome-wide role of PRC2 t...

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Detalles Bibliográficos
Autores principales: Lee, Hun-Goo, Kahn, Tatyana G., Simcox, Amanda, Schwartz, Yuri B., Pirrotta, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510001/
https://www.ncbi.nlm.nih.gov/pubmed/25986499
http://dx.doi.org/10.1101/gr.188920.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510001/
https://www.ncbi.nlm.nih.gov/pubmed/25986499
http://dx.doi.org/10.1101/gr.188920.114

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