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Quantification of GC-biased gene conversion in the human genome

Much evidence indicates that GC-biased gene conversion (gBGC) has a major impact on the evolution of mammalian genomes. However, a detailed quantification of the process is still lacking. The strength of gBGC can be measured from the analysis of derived allele frequency spectra (DAF), but this appro...

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Detalles Bibliográficos
Autores principales: Glémin, Sylvain, Arndt, Peter F., Messer, Philipp W., Petrov, Dmitri, Galtier, Nicolas, Duret, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510005/
https://www.ncbi.nlm.nih.gov/pubmed/25995268
http://dx.doi.org/10.1101/gr.185488.114