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Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth

Lymphoid tissue inducer (LTi) cells are activated by accessory cell IL-23, and promote lymphoid tissue genesis and antibacterial peptide production by the mucosal epithelium. We investigated the role of LTi cells in the gastric mucosa in the context of microbial infection. Mice deficient in IRAK-M,...

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Detalles Bibliográficos
Autores principales: Shiu, Jessica, Piazuelo, M. Blanca, Ding, Hua, Czinn, Steven J., Drakes, Maureen L., Banerjee, Aditi, Basappa, Nisha, Kobayashi, Koichi S., Fricke, W. Florian, Blanchard, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510039/
https://www.ncbi.nlm.nih.gov/pubmed/25603827
http://dx.doi.org/10.1038/mi.2014.132