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Selective transcriptional regulation by Myc: Experimental design and computational analysis of high-throughput sequencing data

The gene expression programs regulated by the Myc transcription factor were evaluated by integrated genome-wide profiling of Myc binding sites, chromatin marks and RNA expression in several biological models. Our results indicate that Myc directly drives selective transcriptional regulation, which i...

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Detalles Bibliográficos
Autores principales: Pelizzola, Mattia, Morelli, Marco J., Sabò, Arianna, Kress, Theresia R., de Pretis, Stefano, Amati, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510069/
https://www.ncbi.nlm.nih.gov/pubmed/26217715
http://dx.doi.org/10.1016/j.dib.2015.02.003