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Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels

Substance P is endogenously released in the adult lamprey spinal cord and accelerates the burst frequency of fictive locomotion. This is achieved by multiple effects on interneurons and motoneurons, including an attenuation of calcium currents, potentiation of NMDA currents and reduction of the reci...

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Detalles Bibliográficos
Autores principales: Thörn Pérez, Carolina, Hill, Russell H., Grillner, Sten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510128/
https://www.ncbi.nlm.nih.gov/pubmed/26197458
http://dx.doi.org/10.1371/journal.pone.0133136