Fetal brain 11β-hydroxysteroid dehydrogenase type 2 selectively determines programming of adult depressive-like behaviors and cognitive function, but not anxiety behaviors in male mice

Stress or elevated glucocorticoids during sensitive windows of fetal development increase the risk of neuropsychiatric disorders in adult rodents and humans, a phenomenon known as glucocorticoid programming. 11β-Hydroxysteroid dehydrogenase type 2 (11β-HSD2), which catalyses rapid inactivation of gl...

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Detalles Bibliográficos
Autores principales: Wyrwoll, Caitlin, Keith, Marianne, Noble, June, Stevenson, Paula L., Bombail, Vincent, Crombie, Sandra, Evans, Louise C., Bailey, Matthew A., Wood, Emma, Seckl, Jonathan R., Holmes, Megan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510145/
https://www.ncbi.nlm.nih.gov/pubmed/26036451
http://dx.doi.org/10.1016/j.psyneuen.2015.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510145/
https://www.ncbi.nlm.nih.gov/pubmed/26036451
http://dx.doi.org/10.1016/j.psyneuen.2015.05.003

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