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Correlation of sensitizing capacity and T-cell recognition within the Bet v 1 family
BACKGROUND: Bet v 1 is the main sensitizing allergen in birch pollen. Like many other major allergens, it contains an immunodominant T cell–activating region (Bet v 1(142-156)). Api g 1, the Bet v 1 homolog in celery, lacks the ability to sensitize and is devoid of major T-cell epitopes. OBJECTIVE:...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mosby
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510200/ https://www.ncbi.nlm.nih.gov/pubmed/25670010 http://dx.doi.org/10.1016/j.jaci.2014.12.1928 |