NKG2D Signaling Leads to NK Cell Mediated Lysis of Childhood AML

Natural killer cells have been shown to be relevant in the recognition and lysis of acute myeloid leukemia. In childhood acute lymphoblastic leukemia, it was shown that HLA I expression and KIR receptor-ligand mismatch significantly impact ALL cytolysis. We characterized 14 different primary childho...

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Detalles Bibliográficos
Autores principales: Schlegel, Patrick, Ditthard, Kerstin, Lang, Peter, Mezger, Markus, Michaelis, Sebastian, Handgretinger, Rupert, Pfeiffer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510257/
https://www.ncbi.nlm.nih.gov/pubmed/26236752
http://dx.doi.org/10.1155/2015/473175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510257/
https://www.ncbi.nlm.nih.gov/pubmed/26236752
http://dx.doi.org/10.1155/2015/473175

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