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Deletion of cyp125 Confers Increased Sensitivity to Azoles in Mycobacterium tuberculosis
Mycobacterium tuberculosis is able to utilize cholesterol as a carbon source, and this ability is linked to its virulence in macrophages and in the mouse model of infection. The M. tuberculosis cytochrome P450 Cyp125 plays a key role in cholesterol metabolism being involved in the first steps of its...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510303/ https://www.ncbi.nlm.nih.gov/pubmed/26197389 http://dx.doi.org/10.1371/journal.pone.0133129 |