The Association of LINE-1 Hypomethylation with Age and Centromere Positive Micronuclei in Human Lymphocytes

Global hypomethylation in white blood cell (WBC) DNA has recently been proposed as a potential biomarker for determining cancer risk through genomic instability. However, the amplitude of the changes associated with age and the impacts of environmental factors on DNA methylation are unclear. In this...

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Detalles Bibliográficos
Autores principales: Cho, Yoon Hee, Woo, Hae Dong, Jang, Yoonhee, Porter, Virginia, Christensen, Sonja, Hamilton, Raymond F., Chung, Hai Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510364/
https://www.ncbi.nlm.nih.gov/pubmed/26196382
http://dx.doi.org/10.1371/journal.pone.0133909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510364/
https://www.ncbi.nlm.nih.gov/pubmed/26196382
http://dx.doi.org/10.1371/journal.pone.0133909

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