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The Association of LINE-1 Hypomethylation with Age and Centromere Positive Micronuclei in Human Lymphocytes
Global hypomethylation in white blood cell (WBC) DNA has recently been proposed as a potential biomarker for determining cancer risk through genomic instability. However, the amplitude of the changes associated with age and the impacts of environmental factors on DNA methylation are unclear. In this...
Autores principales: | Cho, Yoon Hee, Woo, Hae Dong, Jang, Yoonhee, Porter, Virginia, Christensen, Sonja, Hamilton, Raymond F., Chung, Hai Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510364/ https://www.ncbi.nlm.nih.gov/pubmed/26196382 http://dx.doi.org/10.1371/journal.pone.0133909 |
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