Foam Cell Formation In Vivo Converts Macrophages to a Pro-Fibrotic Phenotype

Formation of foam cell macrophages, which sequester extracellular modified lipids, is a key event in atherosclerosis. How lipid loading affects macrophage phenotype is controversial, with evidence suggesting either pro- or anti-inflammatory consequences. To investigate this further, we compared the...

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Detalles Bibliográficos
Autores principales: Thomas, Anita C., Eijgelaar, Wouter J., Daemen, Mat J. A. P., Newby, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510387/
https://www.ncbi.nlm.nih.gov/pubmed/26197235
http://dx.doi.org/10.1371/journal.pone.0128163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510387/
https://www.ncbi.nlm.nih.gov/pubmed/26197235
http://dx.doi.org/10.1371/journal.pone.0128163

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