Latent KSHV Infected Endothelial Cells Are Glutamine Addicted and Require Glutaminolysis for Survival

Kaposi’s Sarcoma-associated Herpesvirus (KSHV) is the etiologic agent of Kaposi’s Sarcoma (KS). KSHV establishes a predominantly latent infection in the main KS tumor cell type, the spindle cell, which is of endothelial cell origin. KSHV requires the induction of multiple metabolic pathways, includi...

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Detalles Bibliográficos
Autores principales: Sanchez, Erica L., Carroll, Patrick A., Thalhofer, Angel B., Lagunoff, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510438/
https://www.ncbi.nlm.nih.gov/pubmed/26197457
http://dx.doi.org/10.1371/journal.ppat.1005052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510438/
https://www.ncbi.nlm.nih.gov/pubmed/26197457
http://dx.doi.org/10.1371/journal.ppat.1005052

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